Viagra and Alcohol Interaction

Viagra may interact with alcohol and lead to unpleasant conditions. Alcohol is able to enlarge the hypotensive effects (blood pressure lowering effects) of Viagra, because the medication and alcohol are mild systemic vasodilators.
In clinical pharmacology studies using PDE5 inhibitors more participants consumed alcohol at a dose of 0.7 g/kg in combination with ED medication had clinically meaningful drops in blood pressure than with alcohol alone.
During post marketing experience there were reports of dizziness, and orthostatic hypotension in some patients taking PDE5 inhibitors including Viagra. It was estimated that Sildenafil in dose of 50 mg did not potentiate the hypotensive effect of alcohol in healthy patients with mean maximum blood alcohol levels of 0.08% and in healthy patients consumed alcohol at a dose of 0.5 g/kg.

So the patients should be warned that excessive consumption of alcohol with Viagra may lead to dangerous side effects and unpleasant conditions. Based on the pharmacology of the Viagra, patients should avoid consuming large amounts of alcohol, which may increase the potential for orthostatic signs and symptoms, including increase in heart rate, decrease in standing blood pressure, dizziness, and headache.

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